Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210647 | 0.87 | TRPV3 (0.46) | KCNH2TRPV3CNR2CNR1KDM1A | |
| SCHEMBL5207199 | 0.83 | KCNH2 (0.51) | KCNH2ACKR3JAK2CNR2CNR1 | |
| SCHEMBL5203000 | 0.80 | KCNH2 (0.46) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5202992 | 0.80 | KCNH2 (0.46) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL14608992 | 0.80 | KCNH2 (0.47) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5206565 | 0.80 | KCNH2 (0.47) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5205158 | 0.80 | KCNH2 (0.47) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5207210 | 0.79 | KDM1A (0.55) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5207439 | 0.78 | KCNH2 (0.50) | KCNH2JAK2KDM1AMAOAMAOB | |
| SCHEMBL5206605 | 0.78 | KCNH2 (0.51) | KCNH2JAK2KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104255-A2 | SUBSTITUTED 2-CYCLOHEXYL-4-PHENYL-1H-IMIDAZOLE DERIVATIVES | NEUROGEN CORPORATION (US) | 2003-12-18 | — | — | WO | claimed |