Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5A | Q9NQR1 | 13/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.53 |
| ▸ | TCF7L2 | Q9NQB0 | 6/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259546 | 0.92 | KMT5A (0.59) | KMT5ACTNNB1TCF7L2CCR4 | |
| SCHEMBL3779862 | 0.82 | EHMT2 (0.68) | KMT5ACTNNB1TCF7L2CCR4 | |
| SCHEMBL3640926 | 0.82 | EHMT2 (0.67) | KMT5A | |
| Hydrochloric Acid SCHEMBL3637894 | 0.81 | EHMT2 (0.67) | KMT5ACTNNB1TCF7L2CCR4 | |
| SCHEMBL7255656 | 0.78 | HRH4 (0.64) | CTNNB1TCF7L2 | |
| SCHEMBL3642575 | 0.78 | CTNNB1 (0.68) | CTNNB1TCF7L2 | |
| SCHEMBL7258161 | 0.75 | CTNNB1 (0.57) | CTNNB1TCF7L2 | |
| SCHEMBL25363673 | 0.74 | KMT5A (0.54) | KMT5ACCR4 | |
| SCHEMBL3779698 | 0.74 | WHR1 (0.67) | KMT5ACCR4 | |
| Hydrochloric Acid SCHEMBL3639996 | 0.73 | WHR1 (0.66) | KMT5ACCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055866-A1 | QUINAZOLINE AND QUINOLINE DERIVATIVE COMPOUNDS AS INHIBITORS OF PROLYLPEPTIDASE, INDUCERS OF APOPTOSIS AND CANCER TREATMENT AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-10 | — | — | WO | disclosed |