Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259550 | 0.91 | HTR4 (0.49) | HTR4 | |
| SCHEMBL6327502 | 0.87 | HTR4 (0.58) | HTR4 | |
| SCHEMBL6333842 | 0.87 | HTR4 (0.58) | HTR4 | |
| SCHEMBL6329052 | 0.80 | HTR4 (0.60) | HTR4 | |
| SCHEMBL6327384 | 0.77 | HTR4 (0.42) | HTR4 | |
| SCHEMBL6329125 | 0.76 | HTR4 (0.57) | HTR4 | |
| SCHEMBL6329778 | 0.76 | HTR4 (0.67) | HTR4 | |
| SCHEMBL6328871 | 0.76 | KDM4E (0.53) | HTR4 | |
| SCHEMBL7389932 | 0.75 | HTR4 (0.73) | HTR4 | |
| SCHEMBL6329824 | 0.75 | HTR4 (0.44) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057688-A2 | OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS | PFIZER JAPAN INC. (JP) | 2003-07-17 | — | — | WO | disclosed |