SCHEMBL7259676

SCHEMBL7259676

CS(=O)(=O)c1ccc(-c2cc(C=O)oc(=O)c2-c2ccc(Cl)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254206 0.83 PTGS2 (0.64) PTGS2
SCHEMBL7254174 0.80 PTGS2 (0.51) PTGS2
SCHEMBL6969456 0.80 PTGS2 (0.71) PTGS2
SCHEMBL7254310 0.72 PTGS2 (0.52) PTGS2
SCHEMBL5708965 0.71 PTGS2 (0.65) PTGS2
SCHEMBL5107053 0.71 PTGS2 (0.74) PTGS2
SCHEMBL5709027 0.70 PTGS2 (0.64) PTGS2
SCHEMBL8644362 0.69 PTGS2 (0.69) PTGS2
SCHEMBL6050826 0.69 PTGS2 (0.56) PTGS2
SCHEMBL5052857 0.69 PTGS2 (0.74) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003006451-A1 4-PHENYLPYRAN-2-ONE DERIVATIVES ALMIRALL PRODESFARMA S.A. (ES) 2003-01-23 WO disclosed