Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730834 | 1.00 | MEN1 (0.44) | MEN1KMT2AFFAR1NPC1RAB9A | |
| SCHEMBL982856 | 0.89 | TSHR (0.46) | HPGDALDH1A1MAOBKDM4EADORA3 | |
| SCHEMBL7339250 | 0.89 | TSHR (0.46) | HPGDALDH1A1MAOBKDM4EADORA3 | |
| SCHEMBL9012682 | 0.89 | TSHR (0.46) | HPGDALDH1A1MAOBKDM4EADORA3 | |
| SCHEMBL11385670 | 0.84 | ESR2 (0.51) | MEN1KMT2AFFAR1NPC1RAB9A | |
| SCHEMBL11759277 | 0.84 | MAOB (0.42) | MAOB | |
| SCHEMBL28978626 | 0.82 | MAOB (0.41) | HPGDALDH1A1MAOBKDM4EADORA3 | |
| SCHEMBL11754951 | 0.81 | GRM2 (0.43) | NPC1RAB9AALDH1A1MAOBKDM4E | |
| SCHEMBL11760427 | 0.81 | GUSB (0.44) | NPC1RAB9AMAOBKDM4EADORA3 | |
| SCHEMBL8019731 | 0.78 | ESR2 (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003044007-A1 | METHOD FOR THE PRODUCTION OF CHIRAL, NON-RACEMIC 5-SUBSTITUTED GAMMA-BUTYROLACTONES | BAYER CROPSCIENCE AG (DE) | 2003-05-30 | — | — | WO | disclosed |
| US-5185349-A | Lowering blood cholesterol levels | WARNER-LAMBERT COMPANY (US) | 1993-02-09 | — | — | US | disclosed |
| US-4247466-A | 5-(4'-HYDROXY-4-BIPHENYLYL)-DIHYDRO-2(3H)-FURANEONE; ANTIINFLAMMATORY AGENTS; ANTICOAGULANTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-27 | — | — | US | disclosed |