SCHEMBL982856

SCHEMBL982856

O=C1CCC(c2ccccc2)O1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
MAOB P27338 8/20 0.46
CYP19A1 P11511 3/20 0.46
AR P10275 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CTRB1 P17538 1/20 0.45
HSD11B1 P28845 2/20 0.41
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAOA P21397 1/20 0.39
PSMB5 P28074 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7339250 1.00 TSHR (0.46) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL9012682 1.00 TSHR (0.46) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL28978626 0.93 MAOB (0.41) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL28730834 0.89 MEN1 (0.44) MAOBCYP19A1ARKDM4EADORA3
SCHEMBL7259690 0.89 MEN1 (0.44) MAOBCYP19A1ARKDM4EADORA3
SCHEMBL28354123 0.88 TSHR (0.43) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL2743656 0.88 TSHR (0.43) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL15883776 0.86 KDM4E (0.42) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL1331244 0.86 KDM4E (0.42) TSHRMAOBCYP19A1ARKDM4E
SCHEMBL8019731 0.80 ESR2 (0.56) CYP19A1ADORA3HSD17B10ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113512300-A High-extrusion-efficiency bamboo-based composite material containing carbon nano tubes and preparation method thereof 浙江巧筑新材料科技有限公司 2021-10-19 CN claimed
CN-108467479-B Toughened 2, 5-furandicarboxylic acid copolyester 成都中科普瑞净化设备有限公司 2021-07-06 CN claimed
US-20090270299-A1 Composition for removing protective layer in fabrication of MEMS and method for removing same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-29 US claimed
WO-2006052985-A1 LACTONES AS NEW OXYGENATE FUEL ADDITIVES, FUELS BASED THEREON AND METHODS FOR USING SAME THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-05-18 WO claimed
US-20060096158-A1 Lactones as new oxygenate fuel additives, fuels based thereon and methods for using same ROBINSON J M 2006-05-11 US claimed
US-6967216-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-11-22 US claimed
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor ASTRAZENECA AB (SE) 2003-12-04 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-6028224-A Fluoxetine process from benzoylpropionic acid SEPRACOR INC. (US) 2000-02-22 US claimed
WO-1999067196-A1 FLUOXETINE PROCESS FROM BENZOYLPROPIONIC ACID SEPRACOR INC. (US) 1999-12-29 WO claimed
US-5936124-A Fluoxetine process from benzoylpropionic acid SEPACOR INC. (US) 1999-08-10 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0692191-A1 UTILIZATION OF PHENYL COMPOUNDS FOR THE CONTROL OF PHYTOPARASITE NEMATODES UNIVERSIDAD DE LA LAGUNA (ES) 1996-01-17 EP claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-5451458-A Electrography XEROX CORPORATION (US) 1995-09-19 US claimed
EP-0240233-A1 Derivatives of benzoquinonyl-phenyl alkanoic acid amide SUNTORY LIMITED (JP) 1987-10-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor NPY5R, NPY1R, NPY2R TSHR 84/4885MAOB 423/4885CYP19A1 805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.