SCHEMBL7259693

SCHEMBL7259693

CCCCC(CC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14779702 0.92 TSHR (0.35) TSHRALDH1A1TDP1THRBFDPS
SCHEMBL14778713 0.90 TSHR (0.40) TSHRTHRBFDPS
SCHEMBL7765579 0.90 ALDH1A1 (0.32) TSHRALDH1A1TDP1
SCHEMBL3254143 0.90 TSHR (0.40) TSHRTHRBFDPS
SCHEMBL14777756 0.90 TSHR (0.40) TSHRTHRBFDPS
SCHEMBL14778386 0.90 TSHR (0.40) TSHRTHRBFDPS
SCHEMBL14779120 0.88 TSHR (0.35) TSHRALDH1A1TDP1LMNATHRB
SCHEMBL10839797 0.83 TSHR (0.37) TSHRTHRBFDPS
SCHEMBL10839120 0.83 TSHR (0.32) TSHRLMNATHRBFDPS
SCHEMBL733382 0.82 ALDH1A1 (0.38) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868155-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN disclosed
EP-2634180-A1 Enzymatic process for the preparation of butyrolactones Lonza Ltd. (CH) 2013-09-04 EP disclosed
CN-103012628-A Solid catalyst for olefin polymerization and process for producing olefin polymer SUMITOMO CHEMICAL CO 2013-04-03 CN disclosed
US-20130072648-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-21 US disclosed
WO-2003044034-A1 HETERODIMERIC CONJUGATES OF NEOMYCIN-CHLORAMPHENICOL HAVING AN ENHANCED SPECIFICITY AGAINST RNA TARGETS AND ITS PREPARATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-05-30 WO disclosed
EP-0869953-A1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF CHONG KUN DANG CORP (KR) 1998-10-14 EP disclosed
WO-1996012716-A1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF CHONG KUN DANG CORP. (KR) 1996-05-02 WO disclosed
EP-0343926-B1 A process for preparing 3-substituted methyl-3-cephem-4-carboxylic acid ASAHI CHEMICAL IND (JP) 1994-04-06 EP disclosed
US-5034521-A Process for preparing 3-substituted methyl-3-cephem-4-carboxylic acid ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-07-23 US disclosed
EP-0343926-A2 A process for preparing 3-substituted methyl-3-cephem-4-carboxylic acid Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-11-29 EP disclosed