SCHEMBL7259694

SCHEMBL7259694

O=C(O)c1cn(-c2ccc(F)c(Cl)c2)cn1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.51
KMO O15229 1/20 0.47
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426056 0.87 NOTUM (0.65) NOTUMKMO
SCHEMBL4434017 0.83 KDM4E (0.48) NOTUM
SCHEMBL24208405 0.82 KMO (0.50) NOTUMKMO
SCHEMBL4425457 0.82 KDM4E (0.41) NOTUM
SCHEMBL4425081 0.82 MAP4K4 (0.51) NOTUM
SCHEMBL5509095 0.81 KDM4E (0.51) NOTUMKMO
SCHEMBL30504030 0.81 KDM4E (0.51) NOTUMKMO
SCHEMBL4428145 0.81 KMO (0.49) NOTUMKMO
SCHEMBL4427736 0.80 NOTUM (0.57) NOTUM
SCHEMBL4423548 0.80 KDM4E (0.48) NOTUMKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051795-A2 RESIN-BONDED ISONITRILES MORPHOCHEM AG (DE) 2003-06-26 WO disclosed