Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368985 | 0.95 | HPGD (0.46) | L3MBTL1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL11269666 | 0.90 | HPGD (0.51) | L3MBTL1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL6368587 | 0.85 | HPGD (0.55) | HPGDSMN1; SMN2KMT2AHSP90AA1TSHR | |
| SCHEMBL6368753 | 0.84 | HPGD (0.57) | HPGDSMN1; SMN2KMT2ALMNAHSP90AA1 | |
| SCHEMBL6374647 | 0.83 | SMN1; SMN2 (0.50) | HPGDSMN1; SMN2KMT2ATP53ALOX15 | |
| SCHEMBL6369872 | 0.83 | HPGD (0.46) | L3MBTL1HPGDSMN1; SMN2HSP90AA1TP53 | |
| SCHEMBL7261988 | 0.82 | L3MBTL1 (0.50) | L3MBTL1HPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6369845 | 0.81 | HPGD (0.44) | HPGDSMN1; SMN2KMT2ATP53ALOX15 | |
| SCHEMBL9053612 | 0.78 | KDM4E (0.42) | L3MBTL1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL6374559 | 0.77 | L3MBTL1 (0.54) | L3MBTL1HPGDSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003072570-A1 | ANTIDIABETIC AGENTS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |