Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256870 | 0.80 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL2928262 | 0.78 | HPGD (0.43) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7256698 | 0.77 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7261196 | 0.76 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL2932783 | 0.76 | HPGD (0.54) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL5133489 | 0.74 | HPGD (0.43) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7255691 | 0.73 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7261149 | 0.72 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7255944 | 0.71 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7261208 | 0.71 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002518-A1 | NOVEL 2,4-DIFLUOROBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | DONG HWA PHARM. IND. CO., LTD. (KR) | 2003-01-09 | — | — | WO | disclosed |