Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090826 | 0.84 | MAPT (0.62) | ARCYP3A4KCNH2NPC1RAB9A | |
| SCHEMBL7265899 | 0.81 | AR (0.58) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1712040 | 0.80 | NOTUM (0.62) | ARNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6709526 | 0.79 | MAOB (0.74) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL509652 | 0.79 | MAOB (0.74) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4328451 | 0.79 | MAOB (0.57) | ARMAOB | |
| SCHEMBL10236929 | 0.78 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11350421 | 0.78 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31451837 | 0.78 | CFTR (0.54) | ARMAPTMRGPRX4MAOBALDH1A1 | |
| SCHEMBL14619126 | 0.78 | NOTUM (0.45) | ARNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080564-A1 | MENTHOL SUBSTITUTED ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |