⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655426 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL302687 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL3450815 | 0.75 | — | — | |
| SCHEMBL30392477 | 0.74 | — | — | |
| SCHEMBL301817 | 0.74 | — | — | |
| SCHEMBL7257502 | 0.72 | — | — | |
| SCHEMBL8851707 | 0.70 | — | — | |
| SCHEMBL8754976 | 0.70 | — | — | |
| SCHEMBL306180 | 0.67 | — | — | |
| SCHEMBL19927007 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646044-B1 | Polymerizing liquid propylene in presence of hydrogen and stereoregular polymerization catalyst in one reactor, feeding product, classified to remove smaller particles, to second reactor for gas phase copolymerization with alpha-olefin | JAPAN POLYCHEM CORPORATION (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6191232-B1 | A PROPYLENE BLOCK COPOLYMER PRODUCED BY CONTINUOUS POLYMERIZATION COMPRISING POLYMER PARTICLES, HAVING RUBBER COMPONENT OF AN ALPHA-OLEFIN HAVING 2 TO 18 CARBON ATOMS; EXCELLENT IN RIGIDITY AND IMPACT RESISTANCE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5859143-A | BLOCK COPOLYMERIZATION REACTION IN PRESENCE OF HYDROGEN AND STEREOSPECIFIC CATALYST CONTAINING COMPOUNDS OF MAGNESIUM, TITANIUM, HALOGEN, ORGANOALUMINUM AND ELECTRON DONOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |