Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058971 | 0.85 | STK17B (0.41) | AAK1CYP17A1MAPKAPK2MAPK14 | |
| SCHEMBL6059191 | 0.82 | MAP4K4 (0.35) | LCKAAK1CYP17A1MAPKAPK2MAPK14 | |
| SCHEMBL1181471 | 0.82 | AAK1 (0.51) | LCKAAK1CA12CA1CA9 | |
| SCHEMBL7416577 | 0.81 | LCK (0.45) | LCKAAK1MAPKAPK2CA12CA1 | |
| SCHEMBL24364156 | 0.79 | MAPKAPK2 (0.40) | LCKMAPKAPK2CA12CA1CA9 | |
| SCHEMBL7412985 | 0.79 | SYK (0.42) | LCKAAK1CYP17A1MAPKAPK2CA12 | |
| SCHEMBL30469570 | 0.79 | MAPKAPK2 (0.40) | LCKMAPKAPK2CA12CA1CA9 | |
| SCHEMBL16786131 | 0.79 | CYP17A1 (0.41) | CYP17A1MAPKAPK2CA12CA1AKT1 | |
| SCHEMBL15614476 | 0.77 | MAPK1 (0.43) | LCKAAK1MAPKAPK2CA12CA1 | |
| SCHEMBL7382657 | 0.76 | NR4A1 (0.39) | MAPKAPK2CA12CA1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013526-A1 | ANTICOAGULANT COMPOUNDS | MERCK & CO. INC. (US) | 2003-02-20 | — | — | WO | disclosed |