Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788115 | 0.89 | CYP4F2 (0.62) | CYP4F2CYP4A11SLC7A5MEP1BCA2 | |
| SCHEMBL27827188 | 0.88 | CYP4F2 (0.58) | CYP4F2CYP4A11SLC7A5MEP1BCA2 | |
| SCHEMBL3156861 | 0.87 | SLC7A5 (0.75) | CYP4F2CYP4A11SLC7A5MEP1BCA2 | |
| SCHEMBL3626627 | 0.85 | SLC6A2 (0.61) | SLC7A5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL27781443 | 0.85 | CYP4F2 (0.61) | CYP4F2CYP4A11SLC7A5MEP1BCA2 | |
| SCHEMBL28281252 | 0.84 | SLC7A5 (0.76) | CYP4F2CYP4A11SLC7A5MAPTRAB9A | |
| SCHEMBL13589439 | 0.84 | SLC7A5 (0.76) | CYP4F2CYP4A11SLC7A5MAPTRAB9A | |
| SCHEMBL15609287 | 0.84 | SLC7A5 (0.76) | CYP4F2CYP4A11SLC7A5MAPTRAB9A | |
| SCHEMBL129801 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11MEP1BCA2MAPT | |
| Hydrochloric Acid SCHEMBL7735284 | 0.83 | SLC7A5 (0.74) | CYP4F2CYP4A11SLC7A5MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132395-B1 | Process for the preparation of a pharmacologically active peptide | PTC PHARMA AG (CH) | 2003-10-29 | — | — | EP | disclosed |