SCHEMBL7260787

SCHEMBL7260787

O=[N+]([O-])c1cccc(C=Cc2ccccc2)c1[N+](=O)[O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
CYP19A1 P11511 2/20 0.52
NFE2L2 Q16236 1/20 0.51
MAOB P27338 1/20 0.49
TSHR P16473 1/20 0.47
GPR35 Q9HC97 1/20 0.47
BACE1 P56817 1/20 0.47
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
POLB P06746 1/20 0.47
SOS1 Q07889 1/20 0.46
FBP1 P09467 1/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
ERN1 O75460 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5442818 0.88 MAPT (0.66) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL1578983 0.88 MAPT (0.66) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL1578978 0.88 MAPT (0.66) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL29594574 0.88 MAPT (0.66) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL27405911 0.87 NFE2L2 (0.47) MAPTCYP19A1NFE2L2MAOBTSHR
SCHEMBL29809086 0.84 CYP19A1 (0.65) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL11307663 0.84 CYP19A1 (0.65) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL11307656 0.84 CYP19A1 (0.65) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL27367337 0.83 MAPT (0.53) MAPTCYP19A1NFE2L2MAOBBACE1
SCHEMBL8855377 0.82 NFE2L2 (0.50) MAPTCYP19A1NFE2L2MAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103430108-B Produce volume holographic pattern, shape or the method for image and the holographic article of generation thereof 沙特基础全球技术有限公司 2016-08-10 CN claimed
US-9164480-B2 Holographic data storage device and method of making GENERAL ELECTRIC COMPANY (US) 2015-10-20 US claimed
CN-103012292-B Synthetic method of dibenzanthracene [b,f][1,2] diazocine UNIV CHANGZHOU 2014-12-31 CN claimed
CN-103430108-A Method of marking holograms SABIC INNOVATIVE PLASTICS IP 2013-12-04 CN claimed
CN-103012292-A Synthetic method of dibenzanthracene [b,f][1,2] diazocine UNIV CHANGZHOU 2013-04-03 CN claimed
CN-1918643-B Novel optical storage materials based on narrowband optical properties GEN ELECTRIC 2013-03-13 CN claimed
CN-1918643-A Novel optical storage materials based on narrowband optical properties GEN ELECTRIC (US) 2007-02-21 CN claimed
CN-110128302-A The method for producing 4,4`- diamino bibenzyl -2,2`- disulfonic acid 浙江大学 2019-08-16 CN disclosed
CN-108003029-A A kind of method for preparing nitro compound using graphene catalysis nitric oxide 南京偌赛医药科技有限公司 2018-05-08 CN disclosed
CN-106674064-A Process for preparing stilbene compounds 财团法人工业技术研究院 2017-05-17 CN disclosed
CN-103430108-B Produce volume holographic pattern, shape or the method for image and the holographic article of generation thereof 沙特基础全球技术有限公司 2016-08-10 CN disclosed
CN-103012292-B Synthetic method of dibenzanthracene [b,f][1,2] diazocine UNIV CHANGZHOU 2014-12-31 CN disclosed
CN-102276471-B Method for preparing nitro compound by using nitrogen suboxide PENG XINHUA 2014-12-03 CN disclosed
WO-1999024394-A9 COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIV PITTSBURGH (US) 2001-05-31 WO disclosed
EP-1028941-A2 COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 2000-08-23 EP disclosed
WO-1999024394-A2 COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 1999-05-20 WO disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0823894-A1 AZOCOMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 1998-02-18 EP disclosed
EP-0365357-A2 Negative-working, photo-polymerizable color proofing film without triplet oxygen quenching HOECHST CELANESE CORPORATION (US) 1990-04-25 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed