Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579991 | 0.85 | STAT3 (0.58) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL5487566 | 0.84 | NPC1 (0.42) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL22389541 | 0.83 | NPC1 (0.33) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL7260900 | 0.83 | STAT3 (0.56) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL22389525 | 0.82 | NPC1 (0.33) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL9514951 | 0.82 | STAT3 (0.58) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL21645270 | 0.82 | NPC1 (0.43) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL8689812 | 0.81 | STAT3 (0.60) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL27989818 | 0.78 | STAT3 (0.42) | SMN1; SMN2NPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL3416774 | 0.78 | STAT3 (0.36) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804439-B1 | BETA, BETA '-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM BETA ,BETA '-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIV BRITISH COLUMBIA (CA) | 2003-09-17 | — | — | EP | disclosed |