SCHEMBL7260902

SCHEMBL7260902

CN(C=NCc1ccccc1)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 2/20 0.48
AOC3 Q16853 1/20 0.45
CYP2C19 P33261 1/20 0.41
CHRM4 P08173 1/20 0.41
DRD2 P14416 1/20 0.41
HTR7 P34969 1/20 0.41
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
G6PC1 P35575 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
LMNA P02545 2/20 0.39
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7260899 1.00 TSHR (0.48) TSHRALDH1A1AOC3CYP2C19CHRM4
SCHEMBL21547592 0.85 ALDH1A1 (0.39) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL17761948 0.82 ALDH1A1 (0.43) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL7265542 0.82 ALDH1A1 (0.43) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL7265536 0.82 ALDH1A1 (0.43) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL18811850 0.80 TSHR (0.52) TSHRALDH1A1AOC3CYP2C19CHRM4
SCHEMBL3068681 0.77 MAPT (0.41) TSHRALDH1A1G6PC1NPC1RAB9A
SCHEMBL3068684 0.77 MAPT (0.41) TSHRALDH1A1G6PC1NPC1RAB9A
SCHEMBL12562413 0.76 ALDH1A1 (0.38) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL4528866 0.73 TSHR (0.58) TSHRALDH1A1AOC3CYP2C19CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684620-B1 ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL ELEMENT PREPARED THEREFROM SANYO CHEMICAL IND LTD (JP) 2003-06-04 EP disclosed
US-5870275-A CONTAINING A QUATERNARY AMIDINE GROUP SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-09 US disclosed
EP-0684620-A1 ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL ELEMENT PREPARED THEREFROM SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-29 EP disclosed
US-5286752-A Antiarrhythmic diarylamidines STERLING WINTHROP INC. (US) 1994-02-15 US disclosed