SCHEMBL7260934

SCHEMBL7260934

c1ccc2c(C3CCN(CCCCCN4CCCCC4)CC3)c[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 6/20 1.00
SLC6A4 P31645 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7259920 0.97 ADRA1D (0.97) ADRA1DSLC6A4
Hydrochloric Acid SCHEMBL7255562 0.95 ADRA1D (1.00) ADRA1DSLC6A4
Hydrochloric Acid SCHEMBL7259157 0.89 ADRA1D (0.90) ADRA1DSLC6A4
SCHEMBL5705177 0.89 SLC6A4 (1.00) ADRA1DSLC6A4
SCHEMBL14280709 0.89 ADRA1D (0.80) ADRA1DSLC6A4
SCHEMBL5705183 0.89 SLC6A4 (1.00) ADRA1DSLC6A4
SCHEMBL14306777 0.88 ADRA1D (0.80) ADRA1DSLC6A4
Hydrochloric Acid SCHEMBL5705146 0.88 SLC6A4 (0.98) ADRA1DSLC6A4
SCHEMBL7259959 0.88 ADRA1D (0.78) ADRA1DSLC6A4
SCHEMBL27467624 0.87 ADRA1D (0.77) ADRA1DSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642228-B1 Treating ocular tension, carcinoma, sarcoma, tumentia, circulatory disease, or hypertension TORAY INDUSTRIES, INC. (JP) 2003-11-04 US disclosed
EP-1106605-A1 ALPHA1B-ADRENERGIC RECEPTOR ANTAGONISTS TORAY INDUSTRIES, INC. (JP) 2001-06-13 EP disclosed