Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257823 | 0.77 | PPARA (0.47) | TP53LMNA | |
| SCHEMBL5100255 | 0.76 | MAPT (0.51) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL5107482 | 0.71 | PPARA (0.53) | MAPTTP53LMNATHRBHDAC1 | |
| SCHEMBL5107727 | 0.70 | MAPT (0.49) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL5101123 | 0.70 | MAPT (0.53) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL5100515 | 0.70 | MAPT (0.53) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL5113230 | 0.70 | MAPT (0.55) | MAPTTP53LMNATHRBHDAC1 | |
| SCHEMBL6912068 | 0.70 | MAPT (0.52) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL7252494 | 0.70 | PPARA (0.47) | TP53LMNA | |
| SCHEMBL5100503 | 0.70 | LMNA (0.54) | MAPTTP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099800-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BICYCLIC ANTIDIABETIC AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-12-04 | — | — | WO | disclosed |