Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5690575 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL2320943 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL2189391 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL17927669 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL8470574 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL16053680 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL2910615 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL28113587 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL3917721 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL17513007 | 0.95 | SLC34A1 (0.54) | SLC34A1LMNAKDM4ECYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257676-A1 | PTFE POLYMER-BASED SLIDING MATERIAL HAVING FILLERS WHICH IMPROVE THE TRIBOLOGICAL PROPERTIES | KS GLEITLAGER GMBH (DE) | 2023-08-17 | — | — | US | claimed |
| CN-108273129-B | Anti-collapsibility and high-strength composite calcium phosphate bone cement and preparation method and application thereof | 暨南大学 | 2020-12-11 | — | — | CN | claimed |
| EP-3609991-A1 | PTFE POLYMER-BASED SLIDING MATERIAL HAVING FILLERS WHICH IMPROVE THE TRIBOLOGICAL PROPERTIES | KS Gleitlager GmbH (DE) | 2020-02-19 | — | — | EP | claimed |
| CN-110367058-A | A kind of double climing high yield cultivating methods of passion fruit bead | 广东沃享农业发展有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-105789621-B | A method of molten state lithium source surface tension is reduced so as to improve anode material for lithium-ion batteries high temperature solid-phase sintering process | 哈尔滨工业大学 | 2018-09-11 | — | — | CN | claimed |
| EP-1753474-B1 | INITIALLY PLASTICALLY DEFORMABLE BONE IMPLANT COMPOSITIONS | SUNSTAR SUISSE SA (CH) | 2018-09-05 | — | — | EP | claimed |
| CN-104812358-B | Curable composition for dental applications and its manufacture method | 可乐丽则武齿科株式会社 | 2017-12-19 | — | — | CN | claimed |
| CN-105789621-A | Method for reducing surface tension of molten-state lithium source so as to improve high-temperature solid phase sintering process of cathode material of lithium ion battery | 哈尔滨工业大学 | 2016-07-20 | — | — | CN | claimed |
| EP-3031479-A1 | Compositions for bone reconstruction | Biomatlante (FR) | 2016-06-15 | — | — | EP | claimed |
| CN-104812358-A | Curable composition for dentistry, and method for producing same | KURARAY NORITAKE DENTAL INC | 2015-07-29 | — | — | CN | claimed |
| US-20050209704-A1 | Porous biocompatible implant material and method for its fabrication | GOLUB CAPITAL MARKETS LLC, AS COLLATERAL AGENT | 2005-09-22 | — | — | US | claimed |
| EP-1575636-A2 | BIODEGRADABLE BIOCOMPATIBLE IMPLANT | Degradable Solutions AG (CH) | 2005-09-21 | — | — | EP | claimed |
| JP-2005519676-A | — | — | 2005-07-07 | — | — | JP | claimed |
| EP-1482996-A1 | POROUS BIOCOMPATIBLE IMPLANT MATERIAL AND METHOD FOR ITS FABRICATION | Degradable Solutions AG (CH) | 2004-12-08 | — | — | EP | claimed |
| WO-2004056405-A2 | BIODEGRADABLE POROUS BONE IMPLANT WITH A BARRIER MEMBRANE SEALED THERETO | DEGRADABLE SOLUTIONS AG (CH) | 2004-07-08 | — | — | WO | claimed |
| EP-1433489-A1 | Biodegradable porous bone implant with a barrier membrane sealed thereto | Degradable Solutions AG (CH) | 2004-06-30 | — | — | EP | claimed |
| WO-2003075975-A1 | POROUS BIOCOMPATIBLE IMPLANT MATERIAL AND METHOD FOR ITS FABRICATION | DEGRADABLE SOLUTIONS AG (CH) | 2003-09-18 | — | — | WO | claimed |
| EP-1344538-A1 | Porous biodegradable implant material and method for its fabrication | Degradable Solutions AG (CH) | 2003-09-17 | — | — | EP | claimed |
| CN-1075358-C | Highly dispersible food additive and food composition containing the same | MARNO CALCIUM CO LTD (JP) | 2001-11-28 | — | — | CN | claimed |
| CN-1093058-A | The mineralising fluorination process and the composition of calcified tissue | AMERICAN DENTAL ASS (US) | 1994-10-05 | — | — | CN | claimed |