SCHEMBL7262248

SCHEMBL7262248

CCC1=C(c2cccc3ccc4ccccc4c23)c2ccccc2[CH]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.35
HSD17B10 Q99714 8/20 0.35
HPGD P15428 5/20 0.35
CYP1A2 P05177 3/20 0.35
THRB P10828 1/20 0.35
TSHR P16473 6/20 0.33
MAPK1 P28482 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
CASP1 P29466 3/20 0.33
HIF1A Q16665 3/20 0.33
ATM Q13315 2/20 0.33
RAB9A P51151 2/20 0.33
CYP3A4 P08684 2/20 0.33
CASP7 P55210 2/20 0.33
TDP1 Q9NUW8 2/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2A6 P11509 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269663 0.88 TDP1 (0.37) ALDH1A1HSD17B10HPGDTSHRL3MBTL1
SCHEMBL7268123 0.80 HSD17B10 (0.40) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL7268103 0.78 CYP1A2 (0.33) ALDH1A1HSD17B10HPGDCYP1A2TSHR
SCHEMBL7262259 0.76 TDP1 (0.36) ALDH1A1HSD17B10HPGDTSHRL3MBTL1
SCHEMBL4622627 0.71 CYP1A2 (0.34) ALDH1A1HPGDCYP1A2TDP1MAPT
SCHEMBL25412675 0.71 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL31171149 0.71 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL28025480 0.71 TP53 (0.38) ALDH1A1HSD17B10HPGDCYP1A2TSHR
SCHEMBL2835702 0.69 HSD17B10 (0.67) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL5691392 0.69 KDM4E (0.35) ALDH1A1HSD17B10TSHRL3MBTL1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656601-B1 Adhesive ethylene copolymer resin compositions and laminates using the same MITSUI CHEMICALS INC. (JP) 2003-12-02 US disclosed
EP-0791628-B1 ADHESIVE ETHYLENIC POLYMER RESIN COMPOSITION AND LAMINATE PRODUCED FROM THE COMPOSITION MITSUI CHEMICALS INC (JP) 2001-11-21 EP disclosed
WO-2001014429-A1 SUPPORTED CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF AND METHOD FOR PRODUCING POLY-1 ALKENES WITH BIMODAL OR MULTIMODAL MOLECULAR WEIGHT DISTRIBUTION BASELL POLYOLEFINE GMBH (DE) 2001-03-01 WO disclosed
US-6183863-B1 ETHYLENE-ALPHA-OLEFIN GRAFT COPOLYMER AND POLYMERIZATION CATALYSTS FOR ADHESIVE LAMINATES MITSUI CHEMICAL INC (JP) 2001-02-06 US disclosed
EP-0931099-A1 METHOD FOR PRODUCING OLEFIN POLYMERS WITH A HIGHER MELTING POINT Basell Polyolefine GmbH (DE) 1999-07-28 EP disclosed
WO-1998040419-A1 METHOD FOR PRODUCING OLEFIN POLYMERS WITH A HIGHER MELTING POINT TARGOR GMBH (DE) 1998-09-17 WO disclosed
EP-0791628-A1 ADHESIVE ETHYLENIC POLYMER RESIN COMPOSITION AND LAMINATE PRODUCED FROM THE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-27 EP disclosed