Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154639 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1CHRM1NPC1CHRM2 | |
| SCHEMBL8297083 | 0.79 | HPGD (0.57) | KDM4EALDH1A1CHRM1NPC1CHRM2 | |
| SCHEMBL29857237 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1CHRM1NPC1CHRM2 | |
| SCHEMBL2129927 | 0.79 | CHRM1 (0.61) | KDM4EALDH1A1CHRM1NPC1CNR1 | |
| SCHEMBL30848453 | 0.75 | HPGD (0.60) | KDM4EALDH1A1NPC1CNR2 | |
| SCHEMBL5259572 | 0.75 | NPC1 (0.60) | ALDH1A1NPC1CNR1CNR2 | |
| SCHEMBL4002313 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1CHRM1NPC1CHRM2 | |
| SCHEMBL5670087 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1CHRM1NPC1HIF1A | |
| SCHEMBL12799245 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1CHRM1NPC1HIF1A | |
| SCHEMBL5670080 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1CHRM1NPC1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614898-B1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6291470-B1 | DELTA-OPIOID ANTAGONIST HAVING HIGH SELECTIVITY AND ACTIVITY, THAT EXHIBITS IMMUNOSUPPRESSIVE ACTION, ANTIALLERGIC ACTION, ANTI-INFLAMMATORY ACTION AND BRAIN CELL-PROTECTING ACTION | TORAY INDUSTRIES, INC. (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6087369-A | AN IMMUNOSUPPRESSIVE AGENT, ANTIALLERGIC AGENT, ANTI-INFLAMMATORY AGENT AND BRAIN CELL-PROTECTING AGENT | TORAY INDUSTRIES, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| US-5852030-A | Indole derivatives, process for producing the same and medicinal uses of the same | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |