SCHEMBL7263152

SCHEMBL7263152

O=[N+]([O-])c1ccc(OC(F)F)c(/C=N/c2ccc(F)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
ALDH1A1 P00352 4/20 0.55
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
HTT P42858 2/20 0.47
GLA P06280 1/20 0.47
HSPB1 P04792 3/20 0.47
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
POLB P06746 1/20 0.44
RAB9A P51151 2/20 0.44
MAOB P27338 1/20 0.43
GAA P10253 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 1/20 0.40
XBP1 P17861 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263154 1.00 MAPT (0.55) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7263178 0.90 MEN1 (0.58) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7263179 0.90 MEN1 (0.58) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7269618 0.89 MEN1 (0.47) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7269612 0.89 MEN1 (0.47) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7268499 0.87 MAPT (0.57) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7269589 0.87 FNTA (0.50) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7268502 0.87 MAPT (0.57) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7269583 0.87 FNTA (0.50) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL7269602 0.85 MEN1 (0.51) MAPTALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653353-B2 Hair styling anionic polymer and fluoroamines mixture improves the holding power of styling resins under high humidity conditions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-11-25 US disclosed
US-20020176834-A1 Cosmetic and personal care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-28 US disclosed