SCHEMBL7269589

SCHEMBL7269589

O=[N+]([O-])c1ccc(OC(F)F)c(C=Nc2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.50
FNTB P49356 1/20 0.50
MAOB P27338 1/20 0.48
MAPT P10636 7/20 0.46
ALDH1A1 P00352 6/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
RAB9A P51151 2/20 0.46
POLB P06746 3/20 0.45
GAA P10253 2/20 0.45
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
GLA P06280 1/20 0.45
HTT P42858 1/20 0.45
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269583 1.00 FNTA (0.50) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7263179 0.87 MEN1 (0.58) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7263178 0.87 MEN1 (0.58) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7263152 0.87 MAPT (0.55) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7263154 0.87 MAPT (0.55) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7269612 0.86 MEN1 (0.47) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7269618 0.86 MEN1 (0.47) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7269602 0.84 MEN1 (0.51) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7269599 0.84 MEN1 (0.51) FNTAFNTBMAOBMAPTALDH1A1
SCHEMBL7268502 0.84 MAPT (0.57) FNTAFNTBMAOBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653353-B2 Hair styling anionic polymer and fluoroamines mixture improves the holding power of styling resins under high humidity conditions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-11-25 US disclosed
US-20020176834-A1 Cosmetic and personal care compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-28 US disclosed