SCHEMBL7263275

SCHEMBL7263275

CCOC(=O)c1cc(C(=O)OCC)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
ALDH1A1 P00352 5/20 0.55
MAPT P10636 2/20 0.55
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
GAA P10253 4/20 0.50
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 2/20 0.49
HSD17B10 Q99714 2/20 0.48
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828639 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL11576424 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL337915 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL4952910 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
Hydrochloric Acid SCHEMBL7196906 0.98 TSHR (0.55) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL1852703 0.92 TSHR (0.53) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL346578 0.91 TSHR (0.67) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL7051803 0.91 TSHR (0.48) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL15920586 0.88 CYP4F2 (0.51) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL5240208 0.87 LCK (0.53) TSHRALDH1A1MAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107163249-A A kind of synthetic method of flower-like structure polyimides 株洲时代新材料科技股份有限公司 2017-09-15 CN disclosed
CN-1111182-C Polyamide acid and polyimide micrograin and method for preparing them SUMITOMO BAKELITE CO (JP) 2003-06-11 CN disclosed
US-20030013817-A1 High temperature ionic polymers and membranes made therefrom LU KELLY (US) 2003-01-16 US disclosed
CN-1246489-A Polyamide acid and polyimide micrograin and method for preparing them SUMITOMO BAKELITE CO (JP) 2000-03-08 CN disclosed
US-5633034-A COATING WITH POLYAMIC ACIDS; IMIDIZING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-05-27 US disclosed