SCHEMBL828639

SCHEMBL828639

CCOC(=O)c1cc(C(=O)OCC)c(C(=O)OCC)cc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
ALDH1A1 P00352 5/20 0.55
MAPT P10636 2/20 0.55
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
GAA P10253 4/20 0.50
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 2/20 0.49
HSD17B10 Q99714 2/20 0.48
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11576424 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL7263275 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL337915 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL4952910 1.00 TSHR (0.57) TSHRALDH1A1MAPTLMNAL3MBTL1
Hydrochloric Acid SCHEMBL7196906 0.98 TSHR (0.55) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL1852703 0.92 TSHR (0.53) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL346578 0.91 TSHR (0.67) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL7051803 0.91 TSHR (0.48) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL15920586 0.88 CYP4F2 (0.51) TSHRALDH1A1MAPTLMNAL3MBTL1
SCHEMBL5240208 0.87 LCK (0.53) TSHRALDH1A1MAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567470-B1 HYDROGENATION OF BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2013-06-05 EP claimed
US-7595420-B2 Hydrogenation of benzene polycarboxylic acids or derivatives thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-09-29 US claimed
US-20060247461-A1 Hydrogenation of benzene polycarboxylic acids or derivatives thereof EXXONMOBIL CHEMICAL PATENTS INC. 2006-11-02 US claimed
CN-116041574-B Catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2024-08-20 CN disclosed
WO-2023072179-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD 中国石油化工股份有限公司 2023-05-04 WO disclosed
CN-116041574-A Catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-05-02 CN disclosed
US-10017448-B2 Process for hydrogenation of benzenepolycarboxylic acids and derivatives thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-10 US disclosed
US-20170291867-A1 Improved Process for Hydrogenation of Benzenepolycarboxylic Acids and Derivatives Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2017-10-12 US disclosed
EP-3212605-A1 IMPROVED PROCESS FOR HYDROGENATION OF BENZENEPOLYCARBOXYLIC ACIDS AND DERIVITIVES THEREOF ExxonMobil Chemical Patents Inc. (US) 2017-09-06 EP disclosed
WO-2016066410-A1 IMPROVED PROCESS FOR HYDROGENATION OF BENZENEPOLYCARBOXYLIC ACIDS AND DERIVITIVES THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-05-06 WO disclosed
EP-1567470-B1 HYDROGENATION OF BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2013-06-05 EP disclosed
US-7355084-B2 Method for hydrogenating organic compounds by means of Ru/SiO2 catalysts BASF AKTIENGESELLSCHAFT (DE) 2008-04-08 US disclosed
US-20060247461-A1 Hydrogenation of benzene polycarboxylic acids or derivatives thereof EXXONMOBIL CHEMICAL PATENTS INC. 2006-11-02 US disclosed
US-20060149097-A1 Hydrogenation processes EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2006-07-06 US disclosed
EP-1578712-A2 HYDROGENATION CATALYST, PREPARATION THEREOF AND HYDROGENATION PROCESSES USING THIS CATALYST ExxonMobil Research and Engineering Company (US) 2005-09-28 EP disclosed
US-6888021-B2 Hydrogenation of benzenepolycarboxylic acids or derivatives thereof using a catalyst containing macropores BASF AKTIENGESELLSCHAFT (DE) 2005-05-03 US disclosed
US-20040199033-A1 Method for hydrogenating organic compounds by means of ru/sio2 catalysts BASF AKTIENGESELLSCHAFT (DE) 2004-10-07 US disclosed
WO-2004046076-A2 HYDROGENATION CATALYST, PREPARATION THEREOF AND HYDROGENATION PROCESSES USING THIS CATALYST EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2004-06-03 WO disclosed
US-20020019559-A1 Hydrogenation of benzenepolycarboxylic acids or derivatives thereof using a catalyst containing macropores BRUNNER MELANIE (DE) 2002-02-14 US disclosed
US-6284917-B1 Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using a catalyst containing macropores BASF AKTIENGESELLSCHAFT (DE) 2001-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060149097-A1 Hydrogenation processes HAO2, HVCN1, AOC3 TSHR 4578/4885ALDH1A1 1483/4885MAPT 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.