Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858088 | 1.00 | ALOX5 (0.33) | ALOX5ESR1NR1I2LTB4R | |
| SCHEMBL7262817 | 0.99 | ALOX5 (0.34) | ALOX5ESR1NR1I2LTB4R | |
| SCHEMBL5854259 | 0.86 | STS (0.34) | ESR1LTB4R | |
| SCHEMBL5854573 | 0.86 | STS (0.34) | ESR1LTB4R | |
| SCHEMBL5857175 | 0.86 | STS (0.34) | ESR1LTB4R | |
| SCHEMBL5854000 | 0.86 | STS (0.34) | ESR1LTB4R | |
| SCHEMBL5854340 | 0.86 | STS (0.34) | ESR1LTB4R | |
| SCHEMBL7124146 | 0.84 | ESR1 (0.47) | ESR1NR1I2 | |
| SCHEMBL7119240 | 0.84 | ESR1 (0.47) | ESR1NR1I2 | |
| SCHEMBL7121851 | 0.84 | ESR1 (0.47) | ESR1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |