Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762621 | 0.88 | CYP2C9 (0.42) | CTSKCTSSCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7674937 | 0.86 | CYP2C9 (0.41) | CTSKCTSSCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8303184 | 0.86 | CYP2C9 (0.50) | CTSKCTSSCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2461102 | 0.82 | CA1 (0.40) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL28272668 | 0.79 | CA1 (0.38) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL6428738 | 0.78 | CYP3A4 (0.42) | CYP2C9CYP2C19CYP3A4GAAMEN1 | |
| SCHEMBL5966252 | 0.78 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL11392432 | 0.78 | CYP3A4 (0.42) | CYP2C9CYP2C19CYP3A4CA1CA2 | |
| SCHEMBL523769 | 0.76 | CTSK (0.46) | CTSKCTSSCYP2C9CYP2C19CA1 | |
| SCHEMBL1111142 | 0.76 | CTSK (0.46) | CTSKCTSSCYP2C9CYP2C19CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |