Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.50 |
| ▸ | FAP | Q12884 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264201 | 0.90 | DPP8 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7265481 | 0.90 | ERAP2 (0.42) | ACE | |
| SCHEMBL7264271 | 0.90 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| Ammonia Solution, Strong SCHEMBL10829251 | 0.89 | ERAP2 (0.42) | ACE | |
| SCHEMBL7265473 | 0.88 | ACE (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7263930 | 0.84 | DPP4 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7272811 | 0.83 | ERAP2 (0.43) | ACE | |
| Lysine SCHEMBL7265717 | 0.83 | ACE (0.43) | DPP8ACE | |
| SCHEMBL10829050 | 0.82 | ACE (0.41) | ACE | |
| Potassium Ion SCHEMBL7265630 | 0.82 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |