Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264201 | 0.89 | DPP8 (0.41) | ACEERAP2ERAP1LNPEPDPP8 | |
| Arginine SCHEMBL7264249 | 0.89 | BDKRB2 (0.38) | ACEERAP2ERAP1LNPEPDPP8 | |
| SCHEMBL7263653 | 0.88 | DPP4 (0.50) | ACEDPP8DPP7DPP4DPP9 | |
| SCHEMBL7265481 | 0.87 | ERAP2 (0.42) | ACEERAP2ERAP1LNPEP | |
| Ammonia Solution, Strong SCHEMBL10829251 | 0.86 | ERAP2 (0.42) | ACEERAP2ERAP1LNPEP | |
| SCHEMBL7263930 | 0.83 | DPP4 (0.41) | ERAP2ERAP1LNPEPDPP8DPP7 | |
| Lysine SCHEMBL7265717 | 0.82 | ACE (0.43) | ACEERAP2ERAP1LNPEPDPP8 | |
| SCHEMBL7272811 | 0.81 | ERAP2 (0.43) | ACEERAP2ERAP1LNPEP | |
| SCHEMBL10829050 | 0.79 | ACE (0.41) | ACEERAP2ERAP1LNPEP | |
| Potassium Ion SCHEMBL7265630 | 0.79 | ACE (0.41) | ACEERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590178-A | DIURETICS | AJINOMOTO COMPANY, INCORPORATED (JP) | 1986-05-20 | — | — | US | disclosed |
| US-4536395-A | DIPEPTIDES | AJINOMOTO CO., INC. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4472381-A | Amino acid derivatives, methods of preparing said derivatives and antihypertensive drugs containing them | AJINOMOTO COMPANY INCORPORATED (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0085488-A2 | Amino acid derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1983-08-10 | — | — | EP | disclosed |