Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.82 |
| ▸ | CHAT | P28329 | 2/20 | 0.78 |
| ▸ | EP300 | Q09472 | 4/20 | 0.77 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.77 |
| ▸ | AURKA | O14965 | 2/20 | 0.77 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.77 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374864 | 0.96 | NAA50 (0.81) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL30761742 | 0.96 | NAA50 (0.81) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL23924590 | 0.96 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL14992960 | 0.96 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL30221076 | 0.96 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| Ammonia Solution, Strong SCHEMBL30231959 | 0.96 | NAA50 (0.80) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL3193375 | 0.96 | NAA50 (0.82) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29652004 | 0.95 | NAA50 (0.80) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL20608400 | 0.95 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29896426 | 0.95 | NAA50 (0.84) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859519-B2 | Methods targeting miR-33 microRNAs for regulating lipid metabolism | THE GENERAL HOSPITAL CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130245093-A1 | METHODS TARGETING MIR-33 MICRORNAS FOR REGULATING LIPID METABOLISM | THE GENERAL HOSPITAL CORPORATION (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2608812-A2 | METHODS TARGETING MIR-33 MICRORNAS FOR REGULATING LIPID METABOLISM | The General Hospital Corporation (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027601-A2 | METHODS TARGETING MIR-33 MICRORNAS FOR REGULATING LIPID METABOLISM | THE GENERAL HOSPITAL CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |