Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358187 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL339072 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL11063311 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL10441515 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL10690177 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL9480353 | 0.75 | CYP1A2 (0.41) | ALDH1A1KMT2AGSK3B | |
| SCHEMBL11281281 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL9617635 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL30422274 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 | |
| SCHEMBL10680094 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAOBHPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870624-B1 | Reversible heat-sensitive recording material | KYODO PRINTING CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| EP-0167900-B1 | PRESSURE-SENSITIVE RECORDING MATERIAL | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |