SCHEMBL7264178

SCHEMBL7264178

Cc1cnc(Br)c(Br)c1C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
UHRF1 Q96T88 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480598 0.81 CCR1 (0.42) CCR1CCR5CCR8NOS3NOS1
SCHEMBL28221709 0.79 CCR1 (0.41) CCR1CCR5CCR8NOS3NOS1
SCHEMBL4124740 0.79 HTT (0.31)
SCHEMBL26616054 0.75 CCR1 (0.38) CCR1CCR5CCR8NOS3NOS1
SCHEMBL30631398 0.75 CCR1 (0.38) CCR1CCR5CCR8NOS3NOS1
SCHEMBL21206805 0.75 LMNA (0.44) CCR1CCR5CCR8NOS3NOS1
SCHEMBL16976166 0.75 CCR1 (0.38) CCR1CCR5CCR8NOS3NOS1
SCHEMBL30631397 0.75 CCR1 (0.38) CCR1CCR5CCR8NOS3NOS1
SCHEMBL3828641 0.75 TSHR (0.35)
SCHEMBL24287645 0.72 CCR1 (0.35) CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006135-B1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN IND LTD (JP) 2003-02-12 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed