Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.70 |
| ▸ | ITGAV | P06756 | 13/20 | 0.70 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.70 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.70 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176984 | 0.84 | ITGB3 (0.80) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176988 | 0.84 | ITGB3 (0.80) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7259145 | 0.83 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176936 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176963 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6176461 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7260158 | 0.81 | ITGB3 (0.76) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7259087 | 0.81 | ITGB3 (0.75) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7264402 | 0.80 | ITGB3 (0.65) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL7260117 | 0.80 | ITGB3 (0.68) | ITGB3ITGAVITGB1ITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645991-B1 | Glycoprotein adhesion receptor antagonists such as 3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl)-butyric acid, used for prophylaxis of tumors, osteoporosis, cardiovascular diseases, fibrosis, inflammation, infections or psoriasis | MERCK PATENT GMBH (DE) | 2003-11-11 | — | — | US | disclosed |