SCHEMBL7264348

SCHEMBL7264348

COc1ccc(-c2ncc(C(=O)NN3CCCCC3)nc2-c2ccc(OC)cc2)cc1.COc1ccc(-c2ncc(C(=O)O)nc2-c2ccc(OC)cc2)cc1

nearest known ligand 0.92

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.92
CNR2 P34972 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456110 0.96 CNR1 (1.00) CNR1CNR2
SCHEMBL6673240 0.88 CNR1 (0.91) CNR1
SCHEMBL6013364 0.87 CNR1 (0.93) CNR1CNR2
SCHEMBL6668995 0.86 CNR1 (0.91) CNR1CNR2
SCHEMBL4455016 0.83 CNR1 (1.00) CNR1
SCHEMBL4462335 0.83 CNR1 (1.00) CNR1CNR2
SCHEMBL4455131 0.82 CNR1 (0.67) CNR1
SCHEMBL7259997 0.81 CNR1 (0.92) CNR1
SCHEMBL4461228 0.81 CNR1 (1.00) CNR1CNR2
SCHEMBL2801501 0.81 CNR1 (1.00) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051850-A1 PYRAZINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRAZENECA AB (SE) 2003-06-26 WO disclosed