Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.93 |
| ▸ | CNR2 | P34972 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462335 | 0.96 | CNR1 (1.00) | CNR1CNR2HTT | |
| SCHEMBL6673240 | 0.90 | CNR1 (0.91) | CNR1 | |
| SCHEMBL6668995 | 0.90 | CNR1 (0.91) | CNR1CNR2 | |
| SCHEMBL7264348 | 0.87 | CNR1 (0.92) | CNR1CNR2 | |
| SCHEMBL4461228 | 0.84 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4455016 | 0.84 | CNR1 (1.00) | CNR1 | |
| SCHEMBL2801501 | 0.84 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4456110 | 0.81 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4456253 | 0.80 | CNR1 (0.66) | CNR1 | |
| SCHEMBL30712642 | 0.80 | CNR1 (0.66) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060134146-A1 | Stable dispersion of solid particles comprising a water-insoluble pyrazine compound | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | US | disclosed |
| WO-2003051850-A1 | PYRAZINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060134146-A1 | Stable dispersion of solid particles comprising a water-insoluble pyrazine compound | SKP1, SPOP, ABCG2 | CNR1 4128/4885CNR2 4310/4885HTT 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.