Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CDH1 | P12830 | 1/20 | 0.56 |
| ▸ | APC | P25054 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269138 | 0.92 | ALDH1A1 (0.66) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15666198 | 0.89 | ALDH1A1 (0.74) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6275897 | 0.84 | ALDH1A1 (0.75) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7269166 | 0.83 | ALDH1A1 (0.57) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7264357 | 0.83 | MEN1 (0.52) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7270537 | 0.82 | ALDH1A1 (0.64) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28565012 | 0.80 | SRD5A2 (0.82) | CHEK2MEN1KMT2AMAPTSRD5A2 | |
| SCHEMBL7269179 | 0.79 | MEN1 (0.50) | CHEK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3919973 | 0.79 | CHEK2 (0.84) | CHEK2MEN1KMT2AMAPTSRD5A2 | |
| SCHEMBL6643380 | 0.79 | CHEK2 (1.00) | CHEK2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552195-B1 | Room temperature initiators for bismaleimide polymerization | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-04-22 | — | — | US | disclosed |