Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567564 | 0.82 | MEN1 (1.00) | TSHRMEN1KMT2AHTTNPSR1 | |
| SCHEMBL8367115 | 0.82 | MEN1 (0.70) | TSHRMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7259937 | 0.79 | RAB9A (0.74) | TSHRMEN1KMT2AHTTNPSR1 | |
| SCHEMBL11710202 | 0.79 | TNF (0.68) | TSHRMEN1KMT2AHTTNPSR1 | |
| SCHEMBL6361819 | 0.78 | RAB9A (0.78) | TSHRMEN1KMT2AHTTNPSR1 | |
| Bromide SCHEMBL11711816 | 0.78 | TNF (0.67) | TSHRMEN1KMT2AHTTNPSR1 | |
| SCHEMBL2900203 | 0.77 | MEN1 (0.66) | TSHRMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL23120167 | 0.77 | TP53 (0.70) | TSHRMEN1KMT2AHTTNPSR1 | |
| SCHEMBL29949283 | 0.77 | TP53 (0.70) | TSHRMEN1KMT2AHTTNPSR1 | |
| Iodide SCHEMBL2892303 | 0.76 | MEN1 (0.64) | TSHRMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064414-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB. (SE) | 2003-08-07 | — | — | WO | disclosed |