Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.62 |
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319098 | 0.87 | ACE (0.51) | ACEACE2 | |
| SCHEMBL8652940 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8654621 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8652937 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8654625 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL29634981 | 0.82 | ACE (0.55) | ACEACE2LTA4H | |
| SCHEMBL6973372 | 0.82 | LTA4H (0.63) | ACEACE2LTA4H | |
| SCHEMBL6979674 | 0.82 | LTA4H (0.63) | ACEACE2LTA4H | |
| SCHEMBL6979678 | 0.82 | LTA4H (0.63) | ACEACE2LTA4H | |
| SCHEMBL8656290 | 0.82 | ACE (0.56) | ACEACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185390-B1 | TRIPEPTIDYL-ARGININALDEHYDE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS THEREOF, AS WELL AS N-(MONOALKYL) AND N,N-DI-(ALKYL)-XXX-L-PROLINE DIPEPTIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-10-02 | — | — | EP | disclosed |
| US-4703036-A | ANTICOAGULANTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-10-27 | — | — | US | disclosed |
| EP-0185390-A2 | Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as N-(monoalkyl) and N,N-di-(alkyl)-Xxx-L-proline dipeptide | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-06-25 | — | — | EP | disclosed |