⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20957514 | 0.80 | — | — | |
| SCHEMBL8907428 | 0.67 | — | — | |
| SCHEMBL5315897 | 0.66 | — | — | |
| SCHEMBL20206954 | 0.66 | — | — | |
| SCHEMBL7164169 | 0.63 | — | — | |
| SCHEMBL11134519 | 0.61 | TDP2 (0.30) | — | |
| SCHEMBL29319531 | 0.61 | — | — | |
| SCHEMBL1305583 | 0.60 | — | — | |
| SCHEMBL31248174 | 0.60 | GSK3A (0.40) | — | |
| SCHEMBL10812661 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238025-B2 | Transdermal preparation comprising a ropinirole derivative | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2016-01-19 | — | — | US | claimed |
| EP-2438917-B1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO (JP) | 2014-09-03 | — | — | EP | claimed |
| US-20120052113-A1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-03-01 | — | — | US | claimed |
| US-9238025-B2 | Transdermal preparation comprising a ropinirole derivative | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2016-01-19 | — | — | US | disclosed |
| US-9238025-B2 | Transdermal preparation comprising a ropinirole derivative | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2438917-B1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-20120052113-A1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-03-01 | — | — | US | disclosed |