Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7265661 | 0.99 | KMT2A (0.59) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10985091 | 0.83 | KMT2A (0.67) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10980359 | 0.83 | MEN1 (0.59) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL10495000 | 0.82 | KMT2A (0.65) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL7272686 | 0.82 | MEN1 (0.57) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Tamolarizine SCHEMBL331314 | 0.81 | KMT2A (0.67) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Tamolarizine SCHEMBL1230722 | 0.80 | MEN1 (0.65) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Tamolarizine SCHEMBL2194434 | 0.80 | MEN1 (0.65) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Tamolarizine SCHEMBL29352586 | 0.80 | MEN1 (0.65) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10988175 | 0.78 | MEN1 (0.59) | KMT2AMEN1OPRM1OPRD1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256890-B1 | PHARMACEUTICAL COMPOSITION FOR PROTECTION OF BRAIN CELLS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4835155-A | Process for protection of brain cells | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0256890-A2 | Pharmaceutical composition for protection of brain cells | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-02-24 | — | — | EP | disclosed |
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |