Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272686 | 0.99 | MEN1 (0.57) | MEN1KMT2AOPRM1OPRD1GAA | |
| SCHEMBL10988175 | 0.89 | MEN1 (0.59) | MEN1KMT2AOPRM1OPRD1GAA | |
| SCHEMBL10987926 | 0.88 | KMT2A (0.50) | MEN1KMT2AOPRM1OPRD1GAA | |
| Hydrochloric Acid SCHEMBL7265013 | 0.87 | KMT2A (0.49) | MEN1KMT2AOPRM1OPRD1GAA | |
| SCHEMBL7265289 | 0.83 | KMT2A (0.60) | MEN1KMT2AOPRM1OPRD1GAA | |
| Hydrochloric Acid SCHEMBL7265661 | 0.82 | KMT2A (0.59) | MEN1KMT2AOPRM1OPRD1GAA | |
| SCHEMBL10986970 | 0.81 | KMT2A (0.55) | MEN1KMT2AOPRM1OPRD1GAA | |
| Hydrochloric Acid SCHEMBL7265511 | 0.81 | KMT2A (0.54) | MEN1KMT2AOPRM1OPRD1GAA | |
| SCHEMBL10985091 | 0.80 | KMT2A (0.67) | MEN1KMT2AOPRM1OPRD1GAA | |
| Tamolarizine SCHEMBL331314 | 0.80 | KMT2A (0.67) | MEN1KMT2AOPRM1OPRD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |