Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7272257 | 0.81 | AOC3 (0.50) | AOC3KDM4EALDH1A1PTGS2MAPT | |
| SCHEMBL12933661 | 0.80 | PTGS2 (0.59) | AOC3KDM4EALDH1A1PTGS2MAPT | |
| SCHEMBL7268018 | 0.80 | KDM4E (0.65) | AOC3KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7266869 | 0.80 | AOC3 (0.49) | AOC3KDM4EALDH1A1PTGS2MAPT | |
| Hydrochloric Acid SCHEMBL7272549 | 0.79 | AOC3 (0.47) | AOC3KDM4EALDH1A1PTGS2MAPT | |
| SCHEMBL19197756 | 0.77 | PTGS2 (0.59) | AOC3PTGS2MAPTHTR2AHTR2C | |
| Acetone SCHEMBL7265054 | 0.76 | KDM4E (0.49) | AOC3KDM4EALDH1A1PTGS2MAPT | |
| SCHEMBL15720901 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1PTGS2MAPTGAA | |
| SCHEMBL3720231 | 0.74 | GAA (0.56) | AOC3KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7338634 | 0.74 | AOC3 (0.62) | AOC3PTGS2MAPTHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718643-B2 | Multimodal anion exchange matrices | CYTIVA BIOPROCESS R&D AB (SE) | 2023-08-08 | — | — | US | disclosed |
| US-11718643-B2 | Multimodal anion exchange matrices | CYTIVA BIOPROCESS R&D AB (SE) | 2023-08-08 | — | — | US | disclosed |
| US-10815269-B2 | Multimodal anion exchange matrices | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2020-10-27 | — | — | US | disclosed |
| US-20190023735-A1 | Multimodal Anion Exchange Matrices | GE HEALTHCARE BIOPROCESS R&D AB (SE) | 2019-01-24 | — | — | US | disclosed |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | GE Healtchare Bio-Sciences AB (SE) | 2015-10-22 | — | — | US | disclosed |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | GE Healtchare Bio-Sciences AB (SE) | 2015-10-22 | — | — | US | disclosed |
| EP-0293925-B1 | COMPOUND ACTIVE IN CARDIOVASCULAR THERAPY | SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. (IT) | 1991-10-16 | — | — | EP | disclosed |
| US-4988735-A | Ethylene diamine active cardiovascular therapy | SIMES (IT) | 1991-01-29 | — | — | US | disclosed |
| EP-0293925-A2 | Compound active in cardiovascular therapy | SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. (IT) | 1988-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815269-B2 | Multimodal anion exchange matrices | H1-3, H1-4, IGF2R | AOC3 2071/4885KDM4E 629/4885ALDH1A1 2226/4885 |
| US-11718643-B2 | Multimodal anion exchange matrices | H1-3, H1-4, IGF2R | AOC3 2071/4885KDM4E 629/4885ALDH1A1 2226/4885 |
| US-20150299248-A1 | Multimodal Anion Exchange Matrices | H1-3, H1-4, IGF2R | AOC3 2071/4885KDM4E 629/4885ALDH1A1 2226/4885 |
| US-20190023735-A1 | Multimodal Anion Exchange Matrices | H1-3, H1-4, IGF2R | AOC3 2071/4885KDM4E 629/4885ALDH1A1 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.