Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370297 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL447135 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL29373398 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL15547394 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HSD17B10L3MBTL1KMT2AMEN1 | |
| SCHEMBL27634502 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL27615461 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL8003388 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL25244833 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL31453778 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL1579492 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045935-A1 | METHOD FOR ALKYLATING THE ALPHA CARBON OF THE 2-METHYLBUTYRATE SECONDARY CHAIN OF LOVASTATIN | FERMIC S.A. DE C.V. (MX) | 2003-06-05 | — | — | WO | disclosed |
| US-6472542-B1 | DECYCLIZATION, AMIDATION, SILATION PROTECTING HYDROXYLS WITH HEXAMETHYIDISILAZANE, METHYLATION, HYDROLYSIS OF AMIDE AND SILANOLS, AMMONIATION, LACTONATION AND RECRYSTALLIZATION; HIGH YIELD AND PURITY | FERMIC S.A. DE C.V. (MX) | 2002-10-29 | — | — | US | disclosed |