SCHEMBL7265484

SCHEMBL7265484

Clc1c[nH+]cc(Cl)c1.F[B-](F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28431559 0.67 TSHR (0.50) TSHRTP53
SCHEMBL28837054 0.65 TSHR (0.47) TSHRTP53CYP3A4
SCHEMBL29253986 0.65 TSHR (0.47) TSHRTP53CYP3A4
SCHEMBL562806 0.63 TSHR (0.37) TSHR
SCHEMBL27399560 0.63 HCAR2 (0.43) TSHR
1,3,5-Trichlorobenzene SCHEMBL429512 0.60
1,3,5-Trichlorobenzene SCHEMBL29043929 0.57 TSHR (0.89) TSHRTP53CYP3A4
1,3,5-Trichlorobenzene SCHEMBL28291993 0.57 TSHR (0.89) TSHRTP53CYP3A4
1,3,5-Trichlorobenzene SCHEMBL28436714 0.57 TSHR (0.89) TSHRTP53CYP3A4
1,3,5-Trichlorobenzene SCHEMBL28192425 0.57 TSHR (0.89) TSHRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006135-B1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN IND LTD (JP) 2003-02-12 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed