Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 12/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275626 | 0.89 | CACNA1F (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7267660 | 0.86 | CACNA1F (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL6951184 | 0.85 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7272104 | 0.83 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7272545 | 0.80 | CACNA1F (0.55) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL7267535 | 0.80 | CACNA1F (0.52) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7273476 | 0.80 | CACNA1F (0.53) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7267362 | 0.80 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7266663 | 0.79 | CACNA1F (0.53) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 | |
| SCHEMBL7272933 | 0.79 | CACNA1F (0.53) | CACNA1FCACNA1DCACNA1SCACNA1CNOTCH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |