Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | SCN1A | P35498 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266702 | 0.87 | CACNA1D (0.58) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL7275922 | 0.84 | CACNA1C (0.55) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL612520 | 0.84 | CACNA1C (0.73) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL4608748 | 0.84 | CACNA1C (0.73) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL7275522 | 0.83 | TSHR (0.41) | CACNA1DCACNA1CADORA3CACNA1FCACNA1S | |
| SCHEMBL7265431 | 0.80 | ADORA3 (0.63) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL9138577 | 0.80 | CACNA1C (0.67) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL7412221 | 0.80 | CACNA1B (0.74) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL7266381 | 0.80 | CACNA1B (0.74) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F | |
| SCHEMBL7272621 | 0.79 | CACNA1D (0.56) | CACNA1BCACNA1DCACNA1CADORA3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920225-A | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0273349-A2 | Resolution of 1,4-dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1988-07-06 | — | — | EP | disclosed |