Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265699 | 1.00 | GSR (0.44) | GSRRNPEPCPB2GABRR1LTA4H | |
| SCHEMBL4349577 | 0.92 | GSR (0.50) | GSRRNPEPCPB2GABRR1LTA4H | |
| SCHEMBL9716838 | 0.88 | GSR (0.46) | GSRRNPEPCPB2GABRR1LTA4H | |
| SCHEMBL9716843 | 0.88 | GSR (0.46) | GSRRNPEPCPB2GABRR1LTA4H | |
| Calcium SCHEMBL32679722 | 0.86 | GSR (0.44) | GSRRNPEPCPB2GABRR1LTA4H | |
| SCHEMBL32679721 | 0.86 | GSR (0.44) | GSRRNPEPCPB2GABRR1LTA4H | |
| SCHEMBL21246737 | 0.83 | GSR (0.42) | GSRRNPEPCPB2GABRR1FOLH1 | |
| SCHEMBL9716745 | 0.82 | GABRR1 (0.41) | GSRRNPEPCPB2GABRR1FOLH1 | |
| SCHEMBL9716741 | 0.82 | GABRR1 (0.41) | GSRRNPEPCPB2GABRR1FOLH1 | |
| SCHEMBL6010162 | 0.81 | GSR (0.43) | GSRRNPEPCPB2FOLH1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638508-B2 | Drug delivery; therapy for liver disorders | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-10-28 | — | — | US | disclosed |
| US-20020009416-A1 | MODIFIED AVIDIN-TYPE MOLECULES AS TARGETING AGENTS FOR THE LIVER AND CELLS OF THE RETICULOENDOTHELIAL SYSTEM | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2002-01-24 | — | — | US | disclosed |
| WO-1997022879-A1 | MODIFIED AVIDIN-TYPE MOLECULES AS TARGETING AGENTS FOR THE LIVER AND CELLS OF THE RETICULOENDOTHELIAL SYSTEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1997-06-26 | — | — | WO | disclosed |