Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716741 | 1.00 | GABRR1 (0.41) | GABRR1CPB2GSRRNPEPGABRR3 | |
| SCHEMBL9716843 | 0.95 | GSR (0.46) | GABRR1CPB2GSRRNPEPCYP2D6 | |
| SCHEMBL9716838 | 0.95 | GSR (0.46) | GABRR1CPB2GSRRNPEPCYP2D6 | |
| Calcium SCHEMBL32679722 | 0.93 | GSR (0.44) | GABRR1CPB2GSRRNPEPCYP2D6 | |
| SCHEMBL32679721 | 0.93 | GSR (0.44) | GABRR1CPB2GSRRNPEPCYP2D6 | |
| SCHEMBL10898039 | 0.82 | ADRA2C (0.43) | HDAC6 | |
| SCHEMBL9716598 | 0.82 | GABRR1 (0.38) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL9716592 | 0.82 | GABRR1 (0.38) | GABRR1CPB2GSRRNPEPBLM | |
| SCHEMBL7265699 | 0.82 | GSR (0.44) | GABRR1CPB2GSRRNPEPCYP2D6 | |
| SCHEMBL7265705 | 0.82 | GSR (0.44) | GABRR1CPB2GSRRNPEPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |