SCHEMBL7265708

SCHEMBL7265708

CCCCS(=O)(=O)NC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.53
PGC P20142 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7275302 0.94 REN (0.56) RENPGC
SCHEMBL7274996 0.93 REN (0.56) RENPGC
SCHEMBL9700486 0.91 REN (0.52) RENPGC
SCHEMBL9700464 0.91 REN (0.52) RENPGC
SCHEMBL7261445 0.91 REN (0.57) RENPGC
SCHEMBL7272695 0.91 REN (0.56) RENPGC
SCHEMBL7266084 0.90 REN (0.56) RENPGC
SCHEMBL7272703 0.90 REN (0.57) RENPGC
SCHEMBL7265370 0.90 REN (0.55) RENPGC
SCHEMBL7301856 0.90 REN (0.52) RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264795-A2 Amino acid derivatives MERCK PATENT GmbH (DE) 1988-04-27 EP disclosed